5-Amino-1MQ

Scientific Data

CAS Number

1380477-12-2

Molecular Formula

C₁₀H₁₁N₂⁺

Molecular Weight

159.21 g/mol

Aliases

5-Amino-1-methylquinolinium, 5-AMQ

Category

Other

Description

5-Amino-1MQ is a small molecule nicotinamide N-methyltransferase (NNMT) inhibitor consisting of a methylated quinolinium structure. Unlike the peptide-based compounds in this library, it is a small molecule that acts by blocking NNMT activity, an enzyme involved in the regulation of NAD⁺ metabolism and methylation pathways. Research has focused on its role in adipocyte differentiation, lipid metabolism, and energy expenditure regulation. Studies have examined its effects on SAM and NAD⁺ availability in the context of metabolic and body composition research. It is supplied in powder form for research purposes.